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Humira (Adalimumab) comes in a carton containing two alcohol pads and two dose trays. Each dose tray consists of a single-use, 1ml pre-filled glass syringe with a fixed 27-gauge 1/2-inch needle, providing 40mg adalimumab dissolved in 0.8ml sterile solution (50mg/ml). Humira is an immune response modifier used to treat rheumatoid arthritis. Humira works by blocking a protein (tumor necrosis factor or TNF) found in the body's immune system that causes joint swelling and damage. HUMIRA is a medicine called a TNF-α blocker, which is a type of protein that blocks the action of a substance your body makes, called TNF-α. TNF-α is made by your body's immune system. People with rheumatoid arthritis (RA) have too much of it in their bodies. The extra TNF-α in your body can attack normal healthy body tissues and cause inflammation especially in the tissues in your bones, cartilage, and joints. HUMIRA can block the damage that too much TNF-α can cause, and it can also lower your body's ability to fight infections. HUMIRA helps reduce the signs and symptoms of RA, such as pain and swollen joints, and may help prevent further damage to your bones and joints. HUMIRA is used in adults with moderate to severe RA who have had a poor response to one or more DMARDs (disease-modifying antirheumatic drugs). HUMIRA is a biologic disease-modifying antirheumatic drug, also called a DMARD. Biologic DMARDS are among the most recent RA treatments approved by the FDA and are approved for reducing the signs and symptoms, and slowing the progression of structural damage to the joints caused by RA. HUMIRA can be used alone or in combination with methotrexate or other DMARDs that are used to treat RA. You take HUMIRA by giving yourself an injection under the skin, every other week. Ask your doctor to show you or a loved one how to inject HUMIRA. HUMIRA needs to be stored in a refrigerator (2°C - 8°C/36-46°F) in its original container and protected from light until it's used. HUMIRA should never be put in the freezer or frozen. Refrigerated HUMIRA remains stable until the expiration date printed on the pre-filled syringe. If you need to take it with you, such as when you're traveling, store it in a cool carrier with an ice pack and protect it from light. |