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Zoledronic Acid injection is a treatment for certain cancers that have spread to the bones. Zoledronic Acid is not chemotherapy and is used along with other cancer treatments, such as radiation, hormonal therapy, or chemotherapy.
The FDA and Health Canada have approved zoledronic acid for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard cancer therapy. Prostate cancer should have progressed after treatment with at least one hormonal therapy Zoledronic Acid injections belong to a class of drugs called bisphosphonates (biss-foss-fon-ates) that slows the bone-destroying activity that occurs with bone metastases. Bisphosphonates directly work against the abnormal cells that cause the "wearing away" of bone and help slow down the abnormal build-up of unstable bone. Bisphosphonates are used to help improve bone strength in many diseases associated with bone resorption, including cancer. Other intravenous (IV) bisphosphonates have been used to treat breast cancer or multiple myeloma that has spread to the bone. After preparation, the infusion takes only 15 minutes. Zoledronic Acid is indicated for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. Prostate cancer should have progressed after treatment with at least one hormonal therapy. Zoledronic Acid is indicated for the treatment of hypercalcemia of malignancy. Vigorous saline hydration, an integral part of hypercalcemia therapy, should be initiated promptly and an attempt should be made to restore the urine output to about 2L/ day throughout treatment. Mild or asymptomatic hypercalcemia may be treated with conservative measures (i.e., saline hydration, with or without loop diuretics). Patients should be hydrated adequately throughout the treatment, but overhydration, especially in those patients who have cardiac failure, must be avoided. Diuretic therapy should not be employed prior to correction of hypovolemia. The safety and efficacy of Zoledronic Acid in the treatment of hypercalcemia associated with hyperparathyroidism or with other non-tumor-related conditions has not been established. Side Effects of Zoledronic Acid: The most common side effects are flu-like symptoms that are usually mild and transient. These symptoms include fatigue, nausea, vomiting, bone pain, or lack of appetite; they may start after the 1st infusion and can last 3 to 5 days. These flu-like symptoms usually occur with the 1st, and perhaps 2nd dose. Patients who experience these symptoms usually do not experience them with the 3rd or 4th dose. If necessary, your doctor can prescribe a mild pain reliever to make you more comfortable. Before each infusion, your doctor will do blood tests to monitor your kidney function and will closely watch your response to the injection (zoledronic acid). It is important to keep up with your fluid intake while on Zoledronic Acid therapy. Signs and symptoms of low fluid intake dehydration include thirst, sagging skin, low urine output, and dry mouth. Be sure to drink plenty of water or other fluids. Zoledronic Acid is contraindicated in patients with clinically significant hypersensitivity to zoledronic acid or other bisphosphonates, or any of the excipients in the formulation of Zoledronic Acid. -Zoledronic Acid should not be administered to women who are pregnant due to potential harm to the fetus -Patients with severe kidney problems should not receive Zoledronic Acid injection. In some cases, Zoledronic Acid and other bisphosphonates have been known to cause kidney damage. If you have any kidney problems, your doctor may reduce your dose or determine that injection (zoledronic acid) should not be given -With treatment of Zoledronic Acid it is important to take a multivitamin that contains 400 IU of Vitamin D and an oral calcium supplement of at least 500 mg daily. Zoledronic Acid is not chemotherapy. It is a treatment for bone metastases. Zoledronic Acid is used along with other treatments for cancer, such as chemotherapy, hormonal therapy, or radiation therapy. Zoledronic Acid may be given on the same schedule as your other therapy or at a different time. Your doctor will decide which cancer medications you will continue to take. Buy Zoledronic Acid injections online from Canada for safe and affordable treatments. |
Zometa belongs to the family of Antihypercalcemic agent or bisphosphonates drugs also known as a Bone resorption inhibitor medicine and commonly used for the treatment of a high level of calcium in the blood (hypercalcaemia) caused by changes in the body that happen with cancer. Zometa also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Zometa works by slowing bone breakdown and decreasing the amount of calcium released from the bones into the blood. Zometa is also used for the treatment of cancer known as multiple myeloma “a tumors formed by the cells of the bone marrow” or certain types of bone metastases (the spread of cancer). Zometa always takes under doctor’s guidance. The recommended doses of Zometa will be different for different patients, according to the requirements of each patient; you continue to take it for as long as your doctor prescribes. If you can not tolerate the recommended dosage, your doctor can prescribe a dose that sufficient for you. Take Zometa exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Zometa is also available in generic form known as Zoledronic Acid. Zometa is being manufactured by Novartis Pharmaceutical Corporation and is available in 4mg/vial Injection. Zometa may also be used for relieves other conditions that determined by your doctor or consultant. Effects - How it works in the body Zometa belongs to the family of Antihypercalcemic agent or bisphosphonates drugs also known as a Bone resorption inhibitor medicine and commonly used for the treatment of a high level of calcium in the blood caused by changes in the body that happen with cancer. Zometa also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Zometa works by slowing bone breakdown and decreasing the amount of calcium released from the bones into the blood. Bisphosphonates drugs are used in a variety of metabolic bone disorders. The bone cells continuously deposit and remove calcium and phophorous, stored in a protein network that makes up his structure of the bone. Biphosphonates bind very tightly to the bone preventing removal of calcium from bone cells. This decreases breakdown and turnover of bone in the body and leading to stronger bones. Possible side effects that occurs during the uses of Zometa:
Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Zometa. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Zometa, it is most important that your doctor or health care professional know if you are taking any of the following or other drugs:
You shouldn’t use this medicine without consultation of doctor if you have an allergy to Zometa or any other ingredients of this medicine. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problem liver disease. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problem of Kidney disease. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problem of heart disease or blood disorders. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problem of Poor dental hygiene and Dental procedures or surgery. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problems of Dehydration. You shouldn’t use Zometa without consultation of doctor if you are suffering to the problems of Hyperparathyroidism. You shouldn’t use Zometa without consultation of doctor if you are pregnant or plan to be pregnant. You shouldn’t use Zometa without consultation of doctor if you are suffering to breastfeeding.
From where can one get Zometa? Anyone can buy Zometa from Online Canadian Pharmacy, which is available at a discounted price, 50% off, in Canada, and the best way to get Zometa is by logging on to http://www.onlinecanadarx.com for online orders. This pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order. Why to buy Zometa drug from Canada? It is cheaper to buy Zometa from Online Canadian Pharmacy, because Canadian government regulates the prices of Zometa and also because of the very common reason of exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Zometa from Canada, there by saving a lot of money. |
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