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Brand Depen (Penicillamine) has been discontinued. Please order alternative Cuprimine or generic of Depen.
• Penicillamine is a chelating agent. It attaches to other chemicals in the body, which aids in their removal. • Penicillamine is used to remove excess copper associated with Wilson's disease. It is also used to reduce cystine in the urine and to treat severe rheumatoid arthritis. • Penicillamine may also be used for purposes other than those listed in this medication guide. • You cannot take penicillamine if you have taken it in the past and it has damaged your blood cells. • Before taking penicillamine, tell your doctor if you have kidney disease or any other serious illness. You may not be able to take penicillamine, or you may require a lower dose or special monitoring during therapy. • Penicillamine may cause birth defects in an unborn baby. However, it has also been used during pregnancy with no evidence of defects. Penicillamine should not be used during pregnancy except to treat Wilson's disease and some cases of cystine in the urine. Do not take this medication without first talking to your doctor if you are pregnant. • It is not known whether penicillamine passes into breast milk. Since penicillamine may harm a nursing infant, breast-feeding is not recommended during treatment with this medication. • If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately: · an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives); · fever or chills; · a sore throat; · unusual bleeding or bruising; · blood in the urine; · unexplained shortness of breath, coughing, or wheezing; · abdominal pain; · yellow skin or eyes; · muscle weakness; or · double vision. • Other, less serious side effects may be more likely to occur. Continue to take penicillamine and notify your doctor if you experience · itching or a rash; · nausea, vomiting, diarrhea, or decreased appetite; · ringing in the ears; · decreased taste; · sores in the mouth; · poor wound healing; or · increased wrinkling of the skin. |
Depen is belongs to the class of drugs known as a chelating agent and antirheumatic, disease-modifying medicines and commonly used for treatment Wilson's disease and rheumatoid arthritis. Depen/Penicillamine works by reducing the blood levels of certain inflammatory chemicals which the body's immune system produces. Depen comes in category of drugs called Penicillamine also. Depen is being manufactured by Merck Pharmaceuticals and is available in 250mg Tablets. What are the most common problems for which Depen/Penicillamine is used? Depen/Penicillamine is useful for the treatment, prevention and relives of Wilson’s disease (too much copper in the body) and rheumatoid arthritis. Depen/Penicillamine is used for treatment of those people who suffered to the problems of kidney stones. Depen/Penicillamine is also used for treatment and management of those people who suffered to the iron, mercury, arsenic, or lead poisoning problem. Depen/Penicillamine is more useful for those people who suffered to the problems of a disease where copper is deposited in the liver and brain. Depen/Penicillamine is also more useful for those people who suffered to the problems of chronic active hepatitis. Depen/Penicillamine is also more useful for those people who suffered to the problems of Cystinuria (presence of cystine in the urine). Depen/Penicillamine is also more useful for those people who suffered to the problems of inflammatory disease of the joints. Depen/Penicillamine may also be used for relieve other conditions that determined by your doctor or consultant. How does Depen/Penicillamine work? Depen/Penicillamine is a family of drugs known as a chelating agent and antirheumatic, disease-modifying medicines and commonly used for treatment Wilson's disease and rheumatoid arthritis. Depen/Penicillamine works by reducing the blood levels of certain inflammatory chemicals which the body's immune system produces. Depen/Penicillamine belongs to a mixed group of medicines called "disease-modifying anti-rheumatic drugs" (DMARDs). It is not understood exactly how Depen/Penicillamine works when used to treat rheumatoid arthritis and other problems. But, it is known that it reduces the blood levels of certain inflammatory chemicals which the body's immune system produces in rheumatoid arthritis. Once these levels have fallen, the symptoms of swollen joints can subside. Depen/Penicillamine may take up to 3 months to work, but if it has no effect in one year then it should be stopped. Because Depen/Penicillamine binds to copper, it can be used to treat Wilson's disease, where there is a harmful accumulation of copper in the body. By binding to the excess copper, the copper is prevented from exerting its harmful effects. Is any prescription required to get Depen/Penicillamine? Yes, prescription is necessary, one most not to use Depen/Penicillamine without prescription. Some times in such conditions Depen/Penicillamine is more harmful for health so, it is better to use Depen/Penicillamine under doctor’s guidance or according to your medical consultant. Dosage of Depen/Penicillamine? Depen/Penicillamine Tablets always take under doctor’s guidance. The recommended starting dosages of Depen/Penicillamine Tablets are taken on an empty stomach (at least 1 hour before meals or 2 hours after meals) but the doses are different for different patients. You continue to take it for as long as your doctor prescribes it, even if you do not feel an immediate benefit. Anybody should take the recommended oral dosage of Depen/Penicillamine Tablets is taking an empty stomach with a full glass of water. What is the minimum duration for which Depen/Penicillamine should be taken? The duration of taking Depen/Penicillamine is not constant; it depends according to the problem. Your doctor or consultant can describe you better about the time period for which duration Depen/Penicillamine should be taken or until the medication is deemed effective. Are there any side effects of Depen/Penicillamine? Possible side effects that occur during the uses of Depen/Penicillamine:
Under what circumstances Depen/Penicillamine should not be used? If you have an allergy to Depen/Penicillamine Tablets or any other ingredients of this medicine, then should not be used. If you have suffering to kidney disease, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the problem liver disease, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the problem heart attack, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the problems of anemia or other blood disorders, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the problems of passing blood in urine, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the fever, skin or mouth problems, Depen/Penicillamine should not be used without consulting of doctor. If you are pregnant or plan to be pregnant, Depen/Penicillamine should not be used without consulting of doctor. If you have suffering to the breastfeeding, Depen/Penicillamine should not be used without consulting of doctor. Under which storage conditions Depen/Penicillamine should be kept? Depen/Penicillamine should be stored in tightly sealed container at room temperature, away from heat, moisture, and direct light. Do not store Depen/Penicillamine Tablets in the bathroom, near the kitchen sink, or in other damp places. Keep always Depen/Penicillamine medicine out of the reach of children.
Similar drugs Depen/Penicillamine
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